U.S. Medication Statistics by State

Data • Stewardship • Informed choice

U.S. Medication Usage by State

Documented medication use rates and overmedication trends by state, correlated with USDA growing zones to show accessible plant-based alternatives.

Purpose: This is not anti-medicine. It's pro-stewardship—showing where prescription rates are highest and what affordable plant-food alternatives can support physician-guided reduction when appropriate.

Key Findings

National Context

  • 70% of Americans take at least one prescription drug (CDC 2023)
  • 46% take at least two; 24% take five or more
  • Most common: antidepressants, opioids, antacids, statins, antidiabetics
  • Cost burden: Americans spend $400+ billion annually on prescription drugs

Overmedication Risks

  • Polypharmacy: 5+ medications increase adverse event risk exponentially
  • Drug-drug interactions: Estimated 100,000+ preventable deaths yearly
  • Deprescribing: Growing physician movement to safely reduce unnecessary medications
  • Preventable disease: 80% of chronic disease is lifestyle-related (food, movement, stress)

State-by-State Overview

The following data shows states with highest prescription rates (by medication class), paired with their USDA growing zones and recommended plants for food-first support.

State Zone(s) Rx Rate Top Medications Food-First Plants
Florida 8–11 High (aging pop.) Antacids, statins, pain meds Turmeric, ginger, leafy greens, sweet potatoes, okra
West Virginia 6–7 Highest national Opioids, antidepressants Garlic, onions, cold-hardy greens, root veggies
Kentucky 6–7 Very high Opioids, antacids, antidepressants Turmeric (containers), ginger (containers), chamomile, lavender
Ohio 5–6 High Antidepressants, antacids Chamomile, peppermint, ginger (in pots), rosemary (in pots)
Pennsylvania 5–7 Moderate-high Statins, antacids, antidepressants Garlic, onions, cold-hardy greens, peppermint, chamomile
Indiana 5–6 High Opioids, antidepressants Peppermint, chamomile, cold-tolerant greens
Louisiana 8–9 High Antacids, antidepressants, pain meds Turmeric, ginger, okra, sweet potatoes, leafy greens
Alabama 7–9 High Opioids, antacids, antidepressants Turmeric (zone 8+), ginger, greens, peppers, sweet potatoes
New Jersey 6–7 Moderate Statins, antacids, antidepressants Garlic, onions, greens, peppermint, chamomile, cold-hardy herbs
California 9–11 Moderate Statins, antacids, antidepressants Turmeric, ginger, rosemary, lavender, year-round vegetables

Top Medication Classes & Plant-Based Food Support

Antidepressants (SSRIs)

~30 million Americans; highest rates in upper Midwest, West Virginia

Lifestyle root causes: Chronic stress, sleep deprivation, sedentary behavior, refined diet

Food-first plants:

  • Tulsi (Holy Basil) – adaptogen; gentle mood & nervous system support
  • Peppermint – calming tea
  • Omega-3 plants: Flax, chia, walnuts (mood & inflammation)
  • B-complex foods: Leafy greens, legumes, whole grains
  • Movement + sleep: Non-negotiable foundational changes

Opioids

~10 million Americans; crisis in Appalachia (WV, KY, OH, PA)

Root causes: Chronic pain from injury, poor posture, inflammation; inadequate physical therapy

Plant-based pain support:

  • Turmeric + black pepper + fat – potent anti-inflammatory
  • Ginger – circulation, inflammation
  • Rosemary – topical oil for massage; circulation
  • Movement: Physical therapy, stretching, walking
  • Sleep: Quality sleep amplifies pain tolerance

Antacids (PPIs)

~20 million Americans; highest in South and Upper Midwest

Root causes: Refined diet, stress, irregular eating, processed foods

Food-first approach:

  • Ginger tea – digestive support before meals
  • Peppermint – calming to GI tract
  • Fermented foods: Sauerkraut, kimchi (beneficial flora)
  • Bone broth – healing to gut lining
  • Whole foods only; eliminate processed + fried

Statins

~30 million Americans; preventive overuse in older populations

Root causes: Inflammatory diet, sedentary, high stress

Food-first support:

  • Oily fish, nuts, seeds – omega-3 fatty acids
  • Garlic, onions – circulation; mild cholesterol support
  • Leafy greens – magnesium, folate
  • Regular movement – most powerful lever
  • Stress management – inflammation driver

Overmedication by Region

Appalachia (WV, KY, OH, PA)

Challenge: Highest opioid + antidepressant rates. Legacy of coal industry injuries, economic decline, and limited access to physical therapy.

Stewardship response: Cold-hardy gardens (zones 5–7) + community-building. Garlic, onions, cold-tolerant greens, peppermint, chamomile grow easily in Appalachian climates. Home food production reduces processed diet; community gardens reduce isolation.

Deep South (WV, KY, LA, AL, MS)

Challenge: High rates of antacids, opioids, antidepressants. High poverty, food deserts, limited preventive care access.

Stewardship response: Warm zones (7–9) allow year-round growing. Turmeric, ginger, okra, sweet potatoes, leafy greens thrive in containers or small yards. Multi-generational family gardening reclaims cultural food traditions and reduces medication dependency.

Upper Midwest (OH, IN, IL, MI)

Challenge: High depression rates (winter, industrial decline), antacid use (processed diet), seasonal affective patterns.

Stewardship response: Zones 5–6 favor cold-hardy herbs + preserved foods. Peppermint, chamomile, garlic, onions, preserved greens. Root cellaring + fermentation culture extends harvest. Greenhouses enable winter tulsi + ginger in containers.

Florida & Sunbelt (FL, AZ, TX)

Challenge: Aging populations, high polypharmacy, antacids, statins, pain medications.

Stewardship response: Year-round growing (zones 8–11). Turmeric, ginger, okra, peppers, sweet potatoes, leafy greens available 11 months/year. Community gardening reduces isolation; multigenerational nutrition improves medication tolerance.

Data Sources & Methodology

  • CDC National Health Interview Survey (NHIS) – medication use prevalence
  • SAMHSA Substance Abuse & Mental Health Services – opioid + depression data by state
  • Kaiser Family Foundation (KFF) – healthcare spending, regional variations
  • National Health Statistics Reports – prescription drug use trends
  • USDA Plant Hardiness Zone Map – growing zone assignments

Caveat: State-level data is aggregated and may mask significant variation by county, race, income, and urban vs. rural status. Use as planning reference; adjust for local conditions.

Next: Interactive Map

A clickable SVG map of the U.S. showing:

  • Medication rate color-coding (low → high)
  • USDA zone overlay
  • Featured plants for that state (turmeric, ginger, herbs, etc.)
  • Link to regional gardening guide + clinician collaboration templates

Coming soon: Embed a responsive SVG map with state tooltips and interactive filtering.

Faithfrontier Stewardship Principle

"Jesus entered the temple and overturned the tables of the money changers."

We do not reject legitimate medicine. We reject dependency-by-default—the assumption that pharmaceuticals are the only pathway to wellness. We champion informed consent, stewardship of the body, and the healing power of food, movement, sleep, and community.

Where pharmaceutical overuse has extracted wealth and health from communities, we propose local food production, clinician partnership, and a return to foundational wellness.

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